Helms MN, Self J.L., Bao H.F., Job L., Jain L., and Eaton D.C.
Dopamine Activates Amiloride-Sensitive Sodium Channel (ENaC) in Alveolar Type Cells Examined in situ. Accepted in Am J Physiol Lung Cell Mol Physiol (Apr 2006)
Johnson MD, Bao HF, Helms MN, Chen XJ, Tigue Z, Jain L, Dobbs LG, Eaton DC. Functional ion channels in pulmonary alveolar type I cells support a role for type I cells in lung ion transport. Proc Natl Acad Sci U S A. 2006 Mar 20; [Epub ahead of print]
PMID: 16549766
Helms MN, Chen XJ, Ramosevac S, Eaton DC, Jain L.
Dopamine Regulation of Amiloride-Sensitive Sodium Channels in Lung Cells. Am J Physiol Lung Cell Mol Physiol. 2006 Apr;290(4):L710-22. PMID: 16284210
Helms MN, Liu L, Liang YY, Al-Khalili O, Vandewalle A, Saxena S, Eaton DC, Ma HP. Phosphatidylinositol-3,4,5-trisphosphate (PIP3) mediates aldosterone
stimulation of epithelial sodium channel (ENAC) and interacts with gamma -ENAC. J Biol Chem. 2005 Dec 9;280(49):40885-91. PMID: 16204229
Helms MN, Yu L, Malik B, Kleinhenz DJ, Hart CM, Eaton DC.
Role of SGK1 in nitric oxide inhibition of ENaC in Na+-transporting epithelia. Am J Physiol Cell Physiol. 2005 Sep;289(3):C717-26. PMID: 15843443
Helms MN, Self J.L., Yu L., Guidot D.M., and Eaton, D.C. Chronic ethanol ingestion impairs sodium permeable non-selective cation channels in alveolar type 1 cells. Alcoholism: Clin Exp Res. abstract 2005 (29S).
Helms MN, Fejes-Toth G, Naray-Fejes-Toth A.
Hormone-regulated transepithelial Na+ transport in mammalian CCD cells requires SGK1 expression. Am J Physiol Renal Physiol. 2003 Mar;284(3):F480-7. PMID: 12429555
Naray-Fejes-Toth A, Helms MN, Stokes JB, Fejes-Toth G.
Regulation of sodium transport in mammalian collecting duct cells by
aldosterone-induced kinase, SGK1: structure/function studies.
Mol Cell Endocrinol. 2004 Mar 31;217(1-2):197-202. PMID: 15134818
Helms MN, Yu, L., Bao H.F., and Eaton D.C.
Aldosterone mediated superoxide production regulates epithelial Na+ channel (ENaC) activity in A6 distal nephron cells. Manuscript in preparation.
Yu, L. Helms MN, Eaton, D.C.
Divalent heavy metals regulate epithelial Na channel (ENaC) activity in A6 cells. Manuscript in preparation.